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Cohort details

Identification
Cohort name: ALSPAC
Country: UK
Principal investigator: George Davey Smith
Contact for environmental exposures: John Henderson (a.j.henderson@bristol.ac.uk)
Basic information
Source population: Region-based
Describe selection:
Geographical coverage: Resident in the former Avon health authority in South-West England
Calendar period: 1991-1992
Enrolment Status: Completed
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy Pregnancy weeks: varied
  • Birth
  • Postnatal
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 14541
  • Fathers: -----
  • Children: 14062
Expected duration of follow-up: unknown
Enrolment criteria: - Inclusion: pregnant women resident in the former Avon health authority in South-West England who were expected to deliver between 1st April 1991 and 31st December 1992.
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures - - - - 11500 11000 9500 8500 7000
Questionnaire Outcomes - - - 14062 11500 11000 9500 8500 7000
Cord Blood       9115          
Blood - - - - - - 630 7400 6085
Urine - - - - - - - 461 3585
Hair - - - - - 4500 4000 - -
Nails - - - - - 4500 4000 - -
Saliva - - - - - - - - 4014
Breast Milk       - - - -    
Father
Questionnaire Exposures - 9957 8621 - 8350 7000 6000 4400 3200
Questionnaire Outcomes - 9957 8621 - 8350 7000 6000 4400 3200
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - 4126 - -
Nails - - - - - - 4121 - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures 13545 13190 12418 - 11200 10000 9500 8800 7000
Questionnaire Outcomes 13545 13190 12418 - 11200 10000 9500 8800 7000
Cord Blood       -          
Blood 6040 7070 8700 - - - - - -
Urine 4425 4070 4020 - - - - - -
Hair - - - - - - 4788 - -
Nails - - - - - - 4817 - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Other information
Have genetic analysis been performed: yes Year planned:
Details: GWAS
Genes:
Addresses available:
  • Home: Residential history
  • Mother work: No
  • Child school: No
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: No
    • Diary: Yes When: At 8 years of age, but data unlikely to be useable
  • Mother
    • Questionnaire: No
    • Diary: No
Sociodemographic variables:
  • Mother's social class: Yes
  • Father's social class: Yes
  • Mother's education: Yes
  • Father's education: Yes
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: Yes
  • Social class coding system: SOC 1990
  • Household income: Yes
  • Parity: Yes
  • Birth order: Yes
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: Yes
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: Yes
    • 24h recall: No
    • Other dietary assessment: Yes day diet diaries at 7, 10 and 13 in children person
    • Child: Yes Timing: 6m, 18 months, 3y, 4y, 7y, 9y, 12y
    • Mother: Yes Timing: and parenter: 32 wks gest, 47 mths pp (postpartum)
  • Assessment of physical exercise: Yes
    • Questionnaire: Yes
    • Measurement: Yes
    • Child: Yes Timing:accelerometers in child at 11, 13, 15years; Child questionnaires: ?
    • Mother: Yes
Medical history:
  • Family history: Yes
  • Pre-Pregnancy medical history: Yes
  • Pregnancy complications:
    • Blood preasure measurements: No
    • Maternal hypertension: Yes
    • Preeclampsia: Yes
  • Maternal allergic history: Yes
  • Maternal pregnancy weight, height: Yes
  • Paternal allergic history: Yes
  • Paternal weight, height: Yes
  • Maternal pre-pregnancy weight, height: Yes
Exposures and Outcomes
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