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Cohort details

Identification
Cohort name: BiB
Country: UK
Principal investigator: John Wright (John.Wright@bradfordhospitals.nhs.uk)
Contact for environmental exposures: Mark Neiuwenhuijsen (mnieuwenhuijsen@creal.cat)
Basic information
Source population: Region-based
Describe selection:
Geographical coverage: Bradford (United Kingdom)
Calendar period: 2007-2010
Enrolment Status: Ongoing
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy Pregnancy weeks: 26-28w
  • Birth
  • Postnatal
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 13000
  • Fathers: 3000
  • Children: 13000
Expected duration of follow-up: 20y
Enrolment criteria: - Inclusion: all women booked to give birth at Bradford Royal Infirmary
- Exclusion: woman who plans to move away from Bradford before the birth
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures - - - - 1000 4000 4000 1000 -
Questionnaire Outcomes - - - 13000 1000 4000 4000 1000 -
Cord Blood       11000          
Blood - - - - - 4000 4000 - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Father
Questionnaire Exposures - - 3000 - 200 200 4000 1000 -
Questionnaire Outcomes - - - - - - - - -
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - 3000 - - - - - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures - - 13000 - 1000 4000 4000 1000 -
Questionnaire Outcomes - - 13000 13000 1000 4000 4000 1000 -
Cord Blood       -          
Blood - - 11000 - - - - - -
Urine - - 8000 - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Other information
Have genetic analysis been performed: ---
Addresses available:
  • Home: Residential history
  • Mother work: Yes
  • Child school: No
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: No
    • Diary: No
  • Mother
    • Questionnaire: Yes When: pregnancy
    • Diary: No
Sociodemographic variables:
  • Mother's social class: Yes
  • Father's social class: Yes
  • Mother's education: Yes
  • Father's education: No
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: Yes
  • Social class coding system: ONS (Office for National Statistics)
  • Household income: Yes
  • Parity: Yes
  • Birth order: Yes
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: Yes
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: Yes
    • 24h recall: No
    • Other dietary assessment: No
    • Child: No
    • Mother: Yes Timing: pregnancy
  • Assessment of physical exercise: Yes
    • Questionnaire: Yes
    • Measurement: No
    • Child: No
    • Mother: Yes Timing:pregnancy
Medical history:
  • Family history: Yes
  • Pre-Pregnancy medical history: No
  • Pregnancy complications:
    • Blood preasure measurements: Yes
    • Maternal hypertension: Yes
    • Preeclampsia: Yes
  • Maternal allergic history: No
  • Maternal pregnancy weight, height: Yes
  • Paternal allergic history: No
  • Paternal weight, height: Yes
  • Maternal pre-pregnancy weight, height: Yes
Exposures and Outcomes
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