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Cohort details

Identification
Cohort name: EDEN
Country: France
Principal investigator: Marie-Aline Charles (marie-aline.charles@inserm.fr)
Contact for environmental exposures: Rémy Slama (remy.slama@ujf-grenoble.fr)
Cohort website: N/A
Basic information
Source population: Hospital-based
Describe selection:
Geographical coverage: Nancy and Poitiers areas
Calendar period: 2003-2006
Enrolment Status: Completed
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy Pregnancy weeks: <24w
  • Birth
  • Postnatal
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 2002
  • Fathers: 1750
  • Children: 1899
Expected duration of follow-up: 5y or more
Enrolment criteria: - Inclusion: presenting in the maternity centre before 24 weeks of amenorrhea
- Inclusion: single pregnancy
- Inclusion: being able to write and read French
- Exclusion: known diabetes before pregnancy
- Exclusion: plan to move out of the region within 3 years after contact date
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures - - - - 1650 1650 1400 o -
Questionnaire Outcomes - - - 1900 1650 1650 1400 o -
Cord Blood       1550          
Blood - - - - - - - o -
Urine - - - - - - - o -
Hair - - - 1800 - 1500 1350 o -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Father
Questionnaire Exposures - 1750 - - - - - o -
Questionnaire Outcomes - - - - - - - - -
Cord Blood       -          
Blood - 1350 - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures - 1900 - 1900 1650 1650 1400 o -
Questionnaire Outcomes - - 1900 - - - 1400 o -
Cord Blood       -          
Blood - 1900 - - - - - - -
Urine - 1900 - - - - - - -
Hair - - - 1900 - - - - -
Nails - - - - - - - - -
Saliva - 1706 - - - - - - -
Breast Milk       1900 - - -    
Other information
Have genetic analysis been performed: planned Year planned:
Details:
Genes:
Addresses available:
  • Home: Residential history
  • Mother work: Yes
  • Child school: No
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: No
    • Diary: No
  • Mother
    • Questionnaire: Yes When: end of 2nd trimester
    • Diary: No
Sociodemographic variables:
  • Mother's social class: Yes
  • Father's social class: Yes
  • Mother's education: Yes
  • Father's education: Yes
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: Yes
  • Social class coding system:
  • Household income: Yes
  • Parity: Yes
  • Birth order: Yes
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: Yes
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: Yes
    • 24h recall: No
    • Other dietary assessment: Yes 3 days food records for the infant
    • Child: Yes Timing: FFQ: at 24m, 36m, 60m; Food records: at 4, 8, 12 months
    • Mother: Yes Timing: FFQ: at inclusion (2nd trimester) and after delivery (at birth)
  • Assessment of physical exercise: Yes
    • Questionnaire: Yes
    • Measurement: No
    • Child: Yes Timing:24m, 36m, 60m
    • Mother: Yes Timing:pregnancy, 5y follow-up
Medical history:
  • Family history: No
  • Pre-Pregnancy medical history: Yes
  • Pregnancy complications:
    • Blood preasure measurements: Yes
    • Maternal hypertension: Yes
    • Preeclampsia: Yes
  • Maternal allergic history: Yes
  • Maternal pregnancy weight, height: Yes
  • Paternal allergic history: Yes
  • Paternal weight, height: Yes
  • Maternal pre-pregnancy weight, height: Yes
Exposures and Outcomes
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