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Cohort details

Identification
Cohort name: ELFE
Country: France
Principal investigator: Marie-Aline Charles (marie-aline.charles@inserm.fr)
Contact for environmental exposures: St├ęphanie Vandentorren (s.vandentorren@invs.sante.fr)
Basic information
Source population: Nation-based
Describe selection:
Geographical coverage: France
Calendar period: 2011-2012
Enrolment Status: Planned
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy
  • Birth
  • Postnatal
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 20000
  • Fathers: 20000
  • Children: 20000
Expected duration of follow-up: 18y (each year)
Enrolment criteria: - Inclusion : all children born in hospital maternity units on a total of 16 days 4 days in each of the 4 different quarters of the inclusion year
- Inclusion: gestational age > or = 22 weeks of amenorhea and weight > or = 500g
- Inclusion: the base panel will be restricted to single or twin births
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures - - - 20000 20000 20000 20000 20000 20000
Questionnaire Outcomes 20000 20000 20000 20000 20000 20000 20000 20000 20000
Cord Blood       10000          
Blood - - - - - - - - -
Urine - - - - - - 10000 10000 -
Hair - - - - - - 10000 - -
Nails - - - - - - - - -
Saliva - - - - - - 10000 - -
Breast Milk       - - - -    
Father
Questionnaire Exposures - - - 20000 20000 - - - -
Questionnaire Outcomes - - - - - - - - -
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures 20000 20000 20000 20000 20000 20000 20000 - -
Questionnaire Outcomes 20000 20000 20000 20000 - - 20000 - -
Cord Blood       -          
Blood - - - 10000 - - - - -
Urine - - - 10000 - - - - -
Hair - - - 10000 - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       6000 - - -    
Other information
Have genetic analysis been performed: ---
Addresses available:
  • Home: Residential history
  • Mother work: No
  • Child school: Yes
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: No
    • Diary: No
  • Mother
    • Questionnaire: No
    • Diary: No
Sociodemographic variables:
  • Mother's social class: Yes
  • Father's social class: Yes
  • Mother's education: Yes
  • Father's education: Yes
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: Yes
  • Social class coding system:
  • Household income: Yes
  • Parity: Yes
  • Birth order: Yes
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: Yes
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: Yes
    • 24h recall: No
    • Other dietary assessment: No
    • Child: Yes Timing: 5-6y
    • Mother: No
  • Assessment of physical exercise: Yes
    • Questionnaire: Yes
    • Measurement: No
    • Child: Yes Timing:each year
    • Mother: No
Medical history:
  • Family history: Yes
  • Pre-Pregnancy medical history: No
  • Pregnancy complications:
    • Blood preasure measurements: No
    • Maternal hypertension: Yes
    • Preeclampsia: Yes
  • Maternal allergic history: No
  • Maternal pregnancy weight, height: Yes
  • Paternal allergic history: No
  • Paternal weight, height: Yes
  • Maternal pre-pregnancy weight, height: Yes
Exposures and Outcomes
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