Home | Contact | About ENRIECO | Disclaimer

Cohort details

Identification
Cohort name: KOALA
Country: Netherlands
Principal investigator: Carel Thijs (C.Thijs@EPID.unimaas.nl)
Contact for environmental exposures: Carel Thijs (C.Thijs@EPID.unimaas.nl)
Basic information
Source population: Region-based
Describe selection:
Geographical coverage: South Netherlands
Calendar period: 2000-2003
Enrolment Status: Completed
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy Pregnancy weeks: 14w
  • Birth
  • Postnatal
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 2834
  • Fathers: 2700
  • Children: 2834
Expected duration of follow-up: >12y
Enrolment criteria: - Inclusion: conventional recruitment group: general population, 14 weeks pregnant, recruited by obstetric practices (n=2343)
- Inclusion: alternative recruitment group: general population, 14 weeks pregnant, recruited via anthroposophic obstetric and general practices, organic food shops, magazines (n=491).
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures 2834 - 2834 2834 2654 2714 2578 2080 -
Questionnaire Outcomes - - - 2834 2654 2714 2578 2080 -
Cord Blood       -          
Blood - - - - - - 820 500 -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - 1600 - - -
Breast Milk       - - - -    
Father
Questionnaire Exposures - - - - - - - 2080 -
Questionnaire Outcomes - - - - - - - - -
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - 1600 - - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures 2834 - 2834 2834 2654 2714 2578 2080 -
Questionnaire Outcomes - - 2834 2834 2654 2714 2578 2080 -
Cord Blood       -          
Blood - - 1350 - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - 1600 - - -
Breast Milk       - 315 - -    
Other information
Have genetic analysis been performed: yes Year planned:
Details: specific genes
Genes: innate immunity pathways; fatty acid desaturases
Addresses available:
  • Home: Residential history
  • Mother work: No
  • Child school: Yes
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: Yes When: 7m, 12m, 24m, 5y, 7y
    • Diary: No
  • Mother
    • Questionnaire: No
    • Diary: No
Sociodemographic variables:
  • Mother's social class: No
  • Father's social class: No
  • Mother's education: Yes
  • Father's education: Yes
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: No
  • Social class coding system:
  • Household income: No
  • Parity: Yes
  • Birth order: Yes
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: Yes
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: Yes
    • 24h recall: No
    • Other dietary assessment: Yes dietary supplement use; origin of food groups(organic, conventional)
    • Child: Yes Timing: 7m, 12m, 24m; 5y, 7y
    • Mother: Yes Timing: 34w pregnancy
  • Assessment of physical exercise: Yes
    • Questionnaire: Yes
    • Measurement: Yes
    • Child: Yes Timing:5y: N=380; 7y: N=700
    • Mother: No
Medical history:
  • Family history: Yes
  • Pre-Pregnancy medical history: Yes
  • Pregnancy complications:
    • Blood preasure measurements: Yes
    • Maternal hypertension: Yes
    • Preeclampsia: Yes
  • Maternal allergic history: Yes
  • Maternal pregnancy weight, height: Yes
  • Paternal allergic history: Yes
  • Paternal weight, height: Yes
  • Maternal pre-pregnancy weight, height: Yes
Exposures and Outcomes
Select exposure or outcome filter

OR




Please select one Exposure or Outcome to show