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Cohort details

Identification
Country: UK
Principal investigator: Claudia Kuehni (kuehni@ispm.unibe.ch)
Contact for environmental exposures: Claudia Kuehni (kuehni@ispm.unibe.ch) Marie-Pierre Strippoli (strippol@ispm.unibe.ch) Cris Dogaru (cdogaru@ispm.unibe.ch)
Basic information
Source population: Region-based
Describe selection:
Geographical coverage: Leicestershire Health area (Leicester City Council, Leicestershire County Council and Rutland County Council)
Calendar period: 1998
Enrolment Status: Completed
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy
  • Birth
  • Postnatal Postnatal months: 12-24m
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 4247
  • Fathers: 4247
  • Children: 5400
Expected duration of follow-up: up to adulthood
Enrolment criteria: - Inclusion: registered in the Leicestershire Health Authority Child Health Database
- Inclusion criteria: born between 1-May-1996 and 31-Apr-1997
- Inclusion criteria: complete birth records available
- Inclusion criteria: born and living in Leicester at time of recruitment (April 1998)
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures - - - 5400 5400 4247 3265 2949 o
Questionnaire Outcomes - - - 5400 5400 4247 3265 2949 o
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - o
Breast Milk       - - - -    
Father
Questionnaire Exposures - - - - - - - - -
Questionnaire Outcomes - - - - - 4247 - - -
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures - - - - - - - - -
Questionnaire Outcomes - - - - - 4247 - - -
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Other information
Have genetic analysis been performed: planned Year planned: 2013
Details:
Genes:
Addresses available:
  • Home: Residential history
  • Mother work: No
  • Child school: Yes
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: Yes When: 4y, 6y, 9y, 13y (tv; outdoor play, vigorous activities)
    • Diary: No
  • Mother
    • Questionnaire: No
    • Diary: No
Sociodemographic variables:
  • Mother's social class: No
  • Father's social class: No
  • Mother's education: Yes
  • Father's education: Yes
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: No
  • Social class coding system:
  • Household income: No
  • Parity: Yes
  • Birth order: Yes
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: No
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: No
    • 24h recall: No
    • Other dietary assessment: Yes type of diet (entirely English; mostly English with Asian; mostly Asian; entirely Asian), fresh fruit (twice daily; daily; 2 to 4 times a week ; less than twice a week)
    • Child: Yes Timing: 4y, 6y
    • Mother: No
  • Assessment of physical exercise: Yes
    • Questionnaire: Yes
    • Measurement: No
    • Child: Yes Timing:6y, 9y, 13y (number of hours per week of vigorous activity)
    • Mother: No
Medical history:
  • Family history: No
  • Pre-Pregnancy medical history: No
  • Pregnancy complications:
    • Blood preasure measurements: No
    • Maternal hypertension: No
    • Preeclampsia: No
  • Maternal allergic history: Yes
  • Maternal pregnancy weight, height: No
  • Paternal allergic history: Yes
  • Paternal weight, height: No
  • Maternal pre-pregnancy weight, height: No
Exposures and Outcomes
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