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Cohort details

Identification
Cohort name: PCB cohort
Country: Slovakia
Principal investigator: Irva Hertz-Picciotto (ihp@ucdavis.edu); Tomas Trnovec (tomas.trnovec@szu.sk)
Contact for environmental exposures: Lubica Palkovicova (lubica.palkovicova@szu.sk); Analyses of organochlorines: Anton Kocan (anton.kocan@szu.sk)
Cohort website: N/A
Basic information
Source population: Region-based
Describe selection:
Geographical coverage: 2 selected regions of eastern Slovakia
Calendar period: 2001-2003
Enrolment Status: Completed
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy
  • Birth
  • Postnatal
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 1134
  • Fathers: 1134
  • Children: 1134
Expected duration of follow-up: 18y
Enrolment criteria: - Inclusion: living in the region at least 5 years prior to pregnancy
- Inclusion: mother at least 18 years old
- Inclusion: maximum of 3 previous deliveries
- Inclusion: no serious illness of mother during pregnancy
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures - - - - 940 820 480 p -
Questionnaire Outcomes - - - 1134 940 820 480 p -
Cord Blood       1104          
Blood - - - - 940 820 480 X -
Urine - - - - - - - X -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Father
Questionnaire Exposures - - - 1134 - - - - -
Questionnaire Outcomes - - - - - - - - -
Cord Blood       -          
Blood - - - - - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures - - - 1134 - - - - -
Questionnaire Outcomes - - - 1134 - - - - -
Cord Blood       -          
Blood - - - 1104 - - - - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - - - -
Breast Milk       930 - - -    
Other information
Have genetic analysis been performed: ---
Addresses available:
  • Home: Residential history
  • Mother work: No
  • Child school: No
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: No
    • Diary: No
  • Mother
    • Questionnaire: No
    • Diary: No
Sociodemographic variables:
  • Mother's social class: No
  • Father's social class: No
  • Mother's education: Yes
  • Father's education: Yes
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: Yes
  • Social class coding system:
  • Household income: No
  • Parity: Yes
  • Birth order: No
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: No
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: Yes
    • 24h recall: No
    • Other dietary assessment: No
    • Child: Yes Timing: 6m, 16m, 45m, 6y
    • Mother: Yes Timing: pregnancy (at delivery)
  • Assessment of physical exercise: No
    • Questionnaire: No
    • Measurement: No
    • Child: No
    • Mother: No
Medical history:
  • Family history: No
  • Pre-Pregnancy medical history: Yes
  • Pregnancy complications:
    • Blood preasure measurements: No
    • Maternal hypertension: Yes
    • Preeclampsia: Yes
  • Maternal allergic history: Yes
  • Maternal pregnancy weight, height: Yes
  • Paternal allergic history: Yes
  • Paternal weight, height: No
  • Maternal pre-pregnancy weight, height: Yes
Exposures and Outcomes
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