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Cohort details

Identification
Cohort name: PIAMA
Country: Netherlands
Principal investigator: Bert Brunekreef (b.brunekreef@uu.nl); Jet Smit (jet.smit@rivm.nl)
Contact for environmental exposures: Ulrike Gehring (u.gehring@uu.nl)
Cohort website: http://piama.iras.uu.nl/
Basic information
Source population: Region-based
Describe selection:
Geographical coverage: A series of communities varying from rural areas to large cities in 3 regions (Northern, Western and Central parts) of the Netherlands
Calendar period: 1996-1997
Enrolment Status: Completed
Developmental period of enrolment:
  • Pre-pregnancy
  • Pregnancy Pregnancy weeks: 3rd trimester
  • Birth
  • Postnatal
Expected number of participants at enrolment when enrolment completed:
  • Mothers: 4146
  • Fathers: 4116
  • Children: 3963
Expected duration of follow-up: 14y
Enrolment criteria: - Usable screening questionnaire
Type of data collection
  Pregnancy Birth Post Natal
  First
trimester
Second
trimester
Third
trimester
  0-6
months
7-18
months
18-60
months
5-10
years
10+
years
Child
Questionnaire Exposures - - - - 3800 3600 3600 3400 2600
Questionnaire Outcomes - - - - 3800 3600 3600 3400 2600
Cord Blood       -          
Blood - - - - 1300 600 750 1750 o
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - 375 - o
Breast Milk       - - - -    
Father
Questionnaire Exposures - - - - - - - - -
Questionnaire Outcomes - - - - 3800 - - - -
Cord Blood       -          
Blood - - - - - 200 300 - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - 564 - -
Breast Milk       - - - -    
Mother
Questionnaire Exposures - - 4100 - - - - - -
Questionnaire Outcomes - - - - 3800 - - - -
Cord Blood       -          
Blood - - - - - 650 800 - -
Urine - - - - - - - - -
Hair - - - - - - - - -
Nails - - - - - - - - -
Saliva - - - - - - 163 - -
Breast Milk       - 250 - -    
Other information
Have genetic analysis been performed: yes Year planned:
Details: specific genes
Genes: GWAS and also specific genes: toll-Like receptor related and genes from T-regulatory pathway
Addresses available:
  • Home: Residential history
  • Mother work: No
  • Child school: Yes
Were these addresses geocoded:
Time activity patterns:
  • Child
    • Questionnaire: Yes When: 5y, 7y, 8y
    • Diary: No
  • Mother
    • Questionnaire: No
    • Diary: No
Sociodemographic variables:
  • Mother's social class: No
  • Father's social class: No
  • Mother's education: Yes
  • Father's education: Yes
  • Mother's ethnic origin: Yes
  • Father's ethnic origin: Yes
  • Maternal age: Yes
  • Paternal age: Yes
  • Social class coding system:
  • Household income: No
  • Parity: Yes
  • Birth order: Yes
  • Child sex: Yes
Breastfeeding:
  • Weeks of breastfeeding: Yes
  • Weeks of exclusive breastfeeding: No
Diet and physical exercise:
  • Dietary assessments: Yes
    • FFQ: Yes
    • 24h recall: No
    • Other dietary assessment: No
    • Child: Yes Timing: Every year
    • Mother: Yes Timing: during pregnancy
  • Assessment of physical exercise: Yes
    • Questionnaire: Yes
    • Measurement: No
    • Child: Yes Timing:5, 7, 8 and 11/12 years
    • Mother: No
Medical history:
  • Family history: Yes
  • Pre-Pregnancy medical history: No
  • Pregnancy complications:
    • Blood preasure measurements: No
    • Maternal hypertension: No
    • Preeclampsia: No
  • Maternal allergic history: Yes
  • Maternal pregnancy weight, height: No
  • Paternal allergic history: Yes
  • Paternal weight, height: Yes
  • Maternal pre-pregnancy weight, height: Yes
Exposures and Outcomes
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